Fuchs’ Dystrophy

What is Fuchs’ Dystrophy?

Fuchs’ Dystrophy is a slow, progressive condition that affects both eyes. The endothelium (innermost layer of the corneal) normally pumps liquid out of the eye, and Fuchs’ Dystrophy occurs when this pumping activity decreases. With less fluid being pumped out of the eye, excess fluid builds up, causing the cornea to become swollen and less transparent, which affects vision. 

Fuchs’ Dystrophy usually starts between the ages of 40 and 50, and typically does not become visually significant until later in life. Women are diagnosed more often than men.

Signs & Symptoms

Patients with Fuchs’ Dystrophy may have blurrier vision in the morning which gradually clears over the course of the day. As Fuchs’ Dystrophy worsens, the blurry vision may remain throughout the day. 

Swelling in Fuchs’ Dystrophy may produce tiny blisters on the corneal surface. When these blisters burst, they may cause pain and irritation. 

Treatment

The treatment for Fuchs’ Dystrophy depends on the severity. In the early stages, hypertonic saline drops or ointments may be used to reduce the corneal swelling, and the occasional and gentle use of a hair dryer may help dry out the blisters. A bandage soft contact lens may help with the discomfort caused by the blisters. 

If a patient begins experiencing vision changes or painful symptoms that interfere with their day-to-day activities, a corneal transplant can be considered. Specifically, an endothelial keratoplasty – either a DSAEK or DMEK – has a high success rate for those with Fuchs’ Dystrophy.

The information contained within these pages is intended for informational purposes only and does not take the place of consulting a physician.
Created by and for New York Cornea, with offices at Columbia University Medical Center and in Scarsdale, New York.
Caring for your corneas since 1988.